Baton Rouge Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a relationship. Inflammation is the body’s response to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it tries to repair itself before the harm was done. Spine & Sports Rehab Center is never shocked at what the body can do! Spine & Sports Rehab Center sees its Baton Rouge chiropractic care as a partner of the body’s system in healing especially when there is spine pain. Chiropractic care utilizes many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is showing value by interrupting the inflammatory process related disc herniation that brings about pain relief: back, neck, spine-related.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are associated with intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body controls itself down to its cellular level via autophagy, the natural process via which the body’s cells clean out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin boosted autophagy and lessened the degradation of the disc’s extracellular matrix (technically indicated by a decline in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin prevents intervertebral disc degeneration by stimulating autophagy. (3) Wow. Spine & Sports Rehab Center is encouraged by this research to see just how well melatonin can perform for Baton Rouge back pain linked to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is such a common malady seen at Spine & Sports Rehab Center that positive news of melatonin’s benefits are quite rousing. A new study explained how melatonin could modulate the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin decreased the inflammatory cell collection and decreased the release of associated inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin interrupted the IL-1B feedback loop, researchers postulated that melatonin may contribute to the restoration process of intervertebral discs after damage has already been done. (1) Spine & Sports Rehab Center will keep following the new research regarding the role inflammation plays in Baton Rouge disc degeneration and melatonin’s role in tackling it.

INFLAMMATION AND MELATONIN

The significance of melatonin in assisting to slow or stop painful conditions due to inflammation is increasing. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other mechanisms is quite fitting. It is also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland produces melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific effect on inflammation and disc degeneration is most attention-getting to Spine & Sports Rehab Center and our Baton Rouge back pain patients.

CONTACT Spine & Sports Rehab Center

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she illustrates how The Cox® Technic System of Spinal Pain Management handles disc degeneration for relief of chronic low back pain in her patient.

Schedule your Baton Rouge chiropractic appointment with Spine & Sports Rehab Center soon. We can talk about the role inflammation plays in your back pain experience and how melatonin may help with the related disc degeneration.

 
Spine & Sports Rehab Center shares new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."